The show follows the lives of Zack and his best friend Quack (who happens to be a duck). All locations are set inside a pop-up book.
- Zack is the main character and a boy with brown hair. His best friend is Quack.
- Quack is a blue duck and the only character who does not talk. Despite this everybody can understand his quacking.
- Kira is an African-American girl with curly hair who can fix anything...with a little paper and glue, that is.
- Hop and Skip are two squirrels.
- Fluffy is a hedgehog.
- Belly-Up is a bullfrog.